Translational Ethics
نویسندگان
چکیده
منابع مشابه
Principlism versus Utilitarianism in Translational Medicine Ethics
Translational medicine is a rather new research area, as it was mentioned for the first time in 1996, in the PubMed publication index, while bearing as a motto “From bench to bedside”. Its complexity and novelty manage to raise a series of problems, in both medical and bioethical terms. The intricacy of translational medicine resides in the implication of several related research areas, such as...
متن کاملThe ethos and ethics of translational research.
Calls for the "translation" of research from bench to bedside are increasingly demanding. What is translation, and why does it matter? We sketch the recent history of outcome-oriented translational research in the United States, with a particular focus on the Roadmap Initiative of the National Institutes of Health (Bethesda, MD). Our main example of contemporary translational research is stem c...
متن کاملTranslational ethics: an analytical framework of translational movements between theory and practice and a sketch of a comprehensive approach
BACKGROUND Translational research in medicine requires researchers to identify the steps to transfer basic scientific discoveries from laboratory benches to bedside decision-making, and eventually into clinical practice. On a parallel track, philosophical work in ethics has not been obliged to identify the steps to translate theoretical conclusions into adequate practice. The medical ethicist A...
متن کاملPredicting Harms and Benefits in Translational Trials: Ethics, Evidence, and Uncertainty
First-in-human clinical trials represent a critical juncture in the translation of laboratory discoveries. However, because they involve the greatest degree of uncertainty at any point in the drug development process, their initiation is beset by a series of nettlesome ethical questions [1]: has clinical promise been sufficiently demonstrated in animals? Should trial access be restricted to pat...
متن کاملMapping the Ethics of Translational Genomics: Situating Return of Results and Navigating the Research-Clinical Divide.
Both bioethics and law have governed human genomics by distinguishing research from clinical practice. Yet the rise of translational genomics now makes this traditional dichotomy inadequate. This paper pioneers a new approach to the ethics of translational genomics. It maps the full range of ethical approaches needed, proposes a "layered" approach to determining the ethics framework for project...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Archives of Surgery
سال: 2000
ISSN: 0004-0010
DOI: 10.1001/archsurg.135.1.39